Ph: 207.396.6433 Fx: 207.396.6436
51 US Route 1 Suite H Scarborough, ME 04074
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Metabolic Leader
We specialize in the diagnosis, treatment, and prevention of metabolic disorders of the endocrine system. Opened on November 15, 2010 by Dr. Stephan Babirak to provide the highest quality patient – focused healthcare in the southern Maine region.

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51 US Route 1, Suite H Scarborough, ME 04074

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**stendra Vs. Viagra: Ultimate Erectile Dysfunction Battle**

Origins and Development of Stendra and Viagra


Stendra (avanafil) was approved for medical use in the United States in 2012 as a new treatment for erectile dysfunction (ED). Developed by Vivus, Inc., it emerged as a next-generation phosphodiesterase type 5 (PDE5) inhibitor, designed to act more rapidly and with fewer side effects compared to earlier drugs. Viagra (sildenafil citrate), developed by Pfizer and approved by the FDA in 1998, was the pioneer of ED medications, quickly becoming a household name and revolutionizing treatment options for men with ED.

Viagra was originally studied for treating hypertension and angina, but during clinical trials, it became evident that it had a significant impact on erectile function. Stendra, on the other hand, was intentionally developed to enhance erectile performance with a focus on faster action and improved tolerability.

Aspect Stendra Viagra
Approval Year 2012 1998
Developer Vivus, Inc. Pfizer
Original Purpose Erectile Dysfunction Hypertension and Angina



Mechanism of Action: How Each Drug Works



When it comes to understanding how these two erectile dysfunction medications work, it’s essential to delve into their biochemical mechanisms. Viagra, known as sildenafil, targets an enzyme called PDE5. By inhibiting this enzyme, Viagra enhances the effects of nitric oxide, leading to increased blood flow to the penis and facilitating an erection during sexual stimulation. Stendra, or avanafil, while also a PDE5 inhibitor, boasts a slightly more selective mechanism. This selectivity allows Stendra to potentially offer fewer side effects and a faster onset of action compared to Viagra.

Both drugs require sexual arousal to be effective, ensuring that their actions are only triggered when needed. However, the distinct molecular structures of Stendra and Viagra influence various factors, from onset time to duration of effectiveness, highlighting crucial differences in their mechanisms. As we explore further, the choice between these medications can be better informed by understanding how each uniquely operates in the body.



Effectiveness: Comparing Performance and Results


When it comes to stendra and Viagra, both have shown significant promise in treating erectile dysfunction, but their performance varies. Clinical studies indicate that stendra typically works faster and is effective within 15 minutes, offering a quicker solution for spontaneous moments. Viagra, on the other hand, takes about 30 to 60 minutes to manifest its effects, which might be a consideration for those seeking immediate results.

In terms of durability, Viagra generally allows for longer-lasting effects, often up to four or five hours. Stendra, however, maintains its effectiveness for a shorter period, around two to three hours. Therefore, the choice between them can hinge on individual preferences regarding onset speed and duration of action.



Onset Time: Speed of Results for Each



Stendra boasts an impressively rapid onset time, often taking effect in just 15 to 30 minutes after ingestion. This swift action can make it a convenient option for those seeking spontaneity. Viagra, on the other hand, typically requires 30 to 60 minutes to become effective, making it slightly slower. While the difference in onset time may seem minor, it can significantly impact the overall experience and planning for intimacy. Users may prefer Stendra if quicker results are a priority.



Side Effects: Weighing the Risks and Benefits


Balancing the side effects is crucial when choosing between Stendra and Viagra for managing erectile dysfunction. Both medications can cause headaches, but Stendra is often noted for having a lower incidence of back pain and muscle aches compared to Viagra. Common side effects for Viagra also include dizziness, vision changes, and nasal congestion, which might be off-putting for some users.

Side Effect Stendra Viagra
Headaches Common Common
Muscle Aches Less Common More Common
Vision Changes Rare Common

While no medication is free of side effects, the severity and frequency can influence one's choice. For instance, Stendra is less likely to cause visual disturbances, making it potentially more appealing to those who prioritize minimal impact on daily activities. Therefore, understanding these differences helps users make an informed decision tailored to their specific health profiles and lifestyle preferences.



Availability and Costs: Accessibility for Users


Access to Stendra and Viagra varies significantly based on geographic location and healthcare infrastructure. While Viagra has been available for over two decades and is recognized globally, it has also become available in less expensive, generic versions. Conversely, Stendra, a newer entrant, might not be as widely available and often comes at a higher cost. Despite this, many users appreciate its rapid onset of action, debating whether the premium price is worth the convenience it provides. Ultimately, insurance coverage, local regulations, and healthcare policies greatly influence the accessibility and affordability of both medications for users.